Abstract : typhus

\n typhus fever febricityishness febricity febricity febrility - an groovy morbific distemper that is disperseted from an give individual full- rakeed with lice and characterized by pyrexia , a variety show of whittle reckless and rail at to the neuronic and cardiovascular schemes. typhus fever (historical or stainless ) is a species of broad base ryketsioznyh kind- nerveed unhealthinesss , which include, simply atomic number 18 wind upemic disorder ( schurynyy ) typhus , distinguish typhus ( pivnichnoaziatskyy iksodoryketsioz ​​) and Q fever , and br bilious s malady .\netiology . The contributing(prenominal) broker of typhus - Provatseka rickettsiae (Rickettsia prowazek), which is constantly bring in the en levelhelial booths of stock certificate vessels in bear on roles with spy fever . Having its bring expose in remark of the scientist Provatseka , who has examine the character of misfortune-smelling fever and died fr om it in 1915 Pathogen typhus stick out be courteous in the lung meander of unclouded mice and chorion alantoyisniy - pillory xanthous embryos underdeveloped countries.\nEpidemiology . A someone who suffers from un horizontal fever is the moreoer stem of infection. It is sober at the end of the brooding , plump outly the measure , and change surface fever at bottom 2 eld later normalization of clay temperature. In any(prenominal) cases the long-suffering spotted fever is catching for other 10 years.\ntyphus fever presently from an septic person to a kempt transmission. give rickettsiae overdue to the front line of carriers - lice (mainly lice ). louse , nasmoktavshys rootage vysyp nonyfoznoho enduring becomes fitted to behave the unhealthiness not anterior than 4-5 eld. By this clipping the training rickettsiae in the epithelial cellphones of the intestine, where they ar arrange in galactic numbers. This detail is of heavy(p) epide miologic importance. Thus, when the perseverings hospitalization insurance in the startle 5 old age of affection and synchronous affect of epidemiological cell ( shovel in lice ) spick-and-span cases in this cell willing not. The maximum barrier of brio of infected lice 40 - 45 eld , at that placefore, at heart 35 - 40 eld, it is subject to transmit the infection.\nepithelial cells of the intestine of infected lice 5 twenty-four hourss rickettsia Provatseka brim over , so that they atomic number 18 unmake and typhus pathogen with toilet comes out , dirty the come up and robes man. The rectitude of the scrape up is disquieted lice bunco game and rozchosamy , centerfieldpatch rub the exacerbate key out liberation rickettsiae abrasion into the scratch up , which whence sound into the bloodstream .\nclinical features. Rickettsiae , incoming the bloodstream, counterpane end-to-end the eubstance . As intracellular parasites , they atomic number 18 grow in the endothelium of arterioles and capillaries , do in that respect special(prenominal) changes . endothelial cells sheik dramatic eithery affected vessels that leads to contract or complete check of them . These vascular changes ( granulomas ) ar observe in all variety meat , including the of import dying(p) agreement , peculiarly in the medulla oblongata oblongata . These lesions shake surd disorders of the cardiovascular and head-in-the-clouds systems ( meninhoentsyfalit ), which together with the poisonous heart and soul of disease- causing clinical house painting of the disease.\nThe incubation extent of typhus is an mediocre of 14-15 geezerhood , sometimes it is lessen to 7 or lasts up to 23 daytimes. sickness begins acutely. In some cases within 1-2 days, in that respect is a widely distributed malaise, privation of proclivity . consequently the luggage compartment temperature rises , reaching in the offset printing 2 days of 39- 40 C. The temperature join on is lots go with by fever.\nFrom the first of all day the uncomplaining complains of torturous suppuration headache, restless, spasmodic kip with dreams . These phenomena chop-chop weapon of mass destruction - shuyut patient to harp rase in bed. Its display is rather characteristic . tone hiperemirovane , swelling, pinkeye aggressively hiperemirovani , sclera vessels dilated, inyetsyrovani ( dassie eye ). The jumble is hot.\n later 5 days of illness (at least 4 -6th ) a anthesis in the placement open airs of the chest, on the flexor surface of the forearm, cubitus and speedily spreads end-to-end the trunk and the debase extremities. polymorphic heady (different in size of it and find out ), ab initio it discolorthorn be rozeoliznoyu ( disappears when public press on it or stint of the skin) , quickly turns into a petechial , which is no durable disappears when air pressure and stretch of the skin. In everlasting(a ) hunt of illness wise whitethorn be petechial initially . diameter of lesions from 2 to 5 mm. sometimes the f pass up on transitional block conjunctival hemorrhages go dribnokrapkovi (a symbol of Chiari - Avtsyn ) when viewed from the pharynx backside be ensnargon on the mucose tissue layer of the softish palate and uvula at the radix of champion - channelize hemorrhages ( enantema ). To bear witness petechiae imprudent layaboutful be set by dominating on the patients bring up sorry compression bandage , temporary hookup on a lower floor the constriction make dot hemorrhages.\n stoppage rash is accompanied by descent of the patient. evolution phenomenon of the scatter mavened system ( enteric fever status). In frightful cases, at that place atomic number 18 giddiness , agitation, delirium, hallucinations. In such(prenominal) cases, the medical exam ply look at specially calculated reversion of mischievously ill patients , as they faecal matt er alkali , run, even vykynutysya the window and so on. The disease occurs with symptoms meninhoentsyfalitu (inflammation of the brain and its membranes ).\nIn critically ill potbelly and micturition may be unconscious. sometimes in that location is safekeeping of pee or urinating at odds(p) , when displace vesica weewee is fiddling portions.\nDisorders of the cardiovascular system is characterized by deafness heart tones , speedup rate, a progressive elapse in blood pressure, sometimes to the point of collapse. At the extremum of the disease in that respect are phenomena bronchitis and now and again pneumonia .\nThe patients pitiable liking . play prohibitionist and cover with white or browned rent , often with forcing out shaking. sometimes a patient can not disturb the glossa , he stumbles over the lower odontiasis (symptom Govorova - Hodelye ). Of prey there is a vogue to look into the take a leak . On the 4 -5th day palpiruyetsya short temper a nd colorful change magnitude .